Untargeted Metabolomics
Detection and quantification of small molecules in your biological fluids and tissue samples
Untargeted Metabolomics Analysis
Metabolites are essential components in all living organisms, and they represent a diverse group of chemical compounds such as amino acids, lipids, organic acids and environmental chemicals. Thousands of metabolites originate from the foods we eat, the microbes in our bodies and many chemical processes that are ongoing in our bodies. It is well known that disorders in metabolite patterns cause metabolic diseases that can have dramatic effects on the survival of the organism.
Therefore, is measuring metabolites essential in today’s clinical chemistry. In addition to use metabolite profiles for screening of metabolic disorders (clinical chemistry applications), targeted or untargeted profiling of metabolites or lipids are necessary also to understand fundamental biological processes. As metabolites can be considered as “endpoints” and closer to the phenotype than e.g., transcript data, metabolite data provides biochemical information that can be linked to particular phenotypes. These links can then be used to connect to gene-, protein- or other meta-data in explorations of targeted biological processes, or also suggested to identify biomarkers.
Metabolomics is to detect and quantify small molecules in biological fluids and tissues. LC-MS global metabolomics platform provides a high-fidelity, reproducible analysis of the current-state of a biological system to help identify pharmacodynamic, efficacy and response biomarkers and reveal changes in key biological pathways.
Service summary
The LC-MS technology involves use of an UHPLC, wherein the individual components in a mixture are first separated followed by ionization and separation of the ions on the basis of their mass/charge (m/z) ratio. LC-MS/MS based Orbitrap technology is used in the Metabolomics test.
- Literature based sample preparation from transferred samples
- Analyzing with Thermo Scientific Orbitrap Exploris 240 MS system
- Metabolite identification with appropriate database using Compound Discoverer software
- Data processing via Compound Discoverer 3.3 software
- Turnover time approx. 2 to 3 weeks**
Sample requirements
Accepted Sample Type
Recommended Amount
Shipment Method
Recommended Extraction Protocol
Plasma
>100ul
Dry ice
After the plasma is separated, it is taken into the appropriate tube and centrifuged at 13000 × g, 15 min, 4 °C. After centrifugation, supernatant is portioned into at least 2 tubes (or more) with 100 µl. Stored at −80 °C until analysis.
Serum
>100ul
Dry ice
After the plasma is separated, it is taken into the appropriate tube and centrifuged at 13000 × g, 15 min, 4 °C. After centrifugation, supernatant is portioned into at least 2 tubes (or more) with 100 µl. Stored at −80 °C until analysis.
Urine
>200ul
Dry ice
After the urine is collected, it is taken into the appropriate tube and centrifuged at 13000 × g, 15 min, 4 °C. After centrifugation, supernatant is portioned into at least 2 tubes (or more) with 200 µl. Stored at −80 °C until analysis.
Stool
>>50mg
Dry ice
Stored at −80 °C until analysis.
CSF
>100ul
Dry ice
Stored at −80 °C until analysis.
Saliva
>100ul
Dry ice
Stored at −80 °C until analysis.
Tissue
>50mg
Dry ice
Stored at −80 °C until analysis.
Cell Pellet
>10⁷ cells
Dry ice
Stored at −80 °C until analysis.
What we do with your samples
Once your samples arrive at Phenome Omics, we start by performing a reception control step in which we make sure the samples meet our requirements.
If the samples fail this quality control step, we will contact you to discuss possible options. If the samples pass reception control, we will inform you and the samples will be queued for sample preparations.
In our laboratory, sample preparation, metabolite identification and data analysis for global metabolomics are performed with state-of-the-art systems. We aim to acquire as much metabolic information as possibble from just a few microliters of sample material.
We use Thermo Scientific Orbitrap Exploris 240 MS for Untargeted Metabolomics Analysis.
This system offers the following qualifications:
· Exceptional mass accuracy
· Ultra-high resolution up to 240k
· Regular & Mild trapping
· Extended low mass to m/z 40
· Robust instrument performance
· AcquireX intelligent acquisition
By means of this technology we are able to use AcquireX Deep Scan for low abundance compounds.
After the metabolomics data is acquired from mass spectrometry, Compound Discoverer 3.3 software is used for data processing. Through the instrumentality of this software, feature detection with integrated databases & spectral library, data reduction, unknown annotations, statistics, pathway mappings are able to carry out.
What can Metabolomics based testing reveal about your health?
Metabolomics testing provides a window into a wide range of physiological processes that can be disrupted in illness and corrected with diet, nutrition, and lifestyle interventions.
Some metabolites have been shown to be associated with various diseases. With metabolite analysis, precautions can be taken before diseases occur.
With the obtained results – detection of increased or decreased metabolites in the blood – we can provide actionable recomendations to you about your lifestyle such as daily diet, exercise frequency, and avoiding stressful environmental conditions.
Science & Innovation
Awards
Omics Library
Language
English
Contact Us
Untargeted Metabolomics
Detection and quantification of small molecules in your biological fluids and tissue samples
Untargeted Metabolomics Analysis
Metabolites are essential components in all living organisms, and they represent a diverse group of chemical compounds such as amino acids, lipids, organic acids and environmental chemicals. Thousands of metabolites originate from the foods we eat, the microbes in our bodies and many chemical processes that are ongoing in our bodies. It is well known that disorders in metabolite patterns cause metabolic diseases that can have dramatic effects on the survival of the organism.
Therefore, is measuring metabolites essential in today’s clinical chemistry. In addition to use metabolite profiles for screening of metabolic disorders (clinical chemistry applications), targeted or untargeted profiling of metabolites or lipids are necessary also to understand fundamental biological processes. As metabolites can be considered as “endpoints” and closer to the phenotype than e.g., transcript data, metabolite data provides biochemical information that can be linked to particular phenotypes. These links can then be used to connect to gene-, protein- or other meta-data in explorations of targeted biological processes, or also suggested to identify biomarkers.
Metabolomics is to detect and quantify small molecules in biological fluids and tissues. LC-MS global metabolomics platform provides a high-fidelity, reproducible analysis of the current-state of a biological system to help identify pharmacodynamic, efficacy and response biomarkers and reveal changes in key biological pathways.
Service summary
The LC-MS technology involves use of an UHPLC, wherein the individual components in a mixture are first separated followed by ionization and separation of the ions on the basis of their mass/charge (m/z) ratio. LC-MS/MS based Orbitrap technology is used in the Metabolomics test.
- Literature based sample preparation from transferred samples
- Analyzing with Thermo Scientific Orbitrap Exploris 240 MS system
- Metabolite identification with appropriate database using Compound Discoverer software
- Data processing via Compound Discoverer 3.3 software
- Turnover time approx. 2 to 3 weeks**
Sample requirements
Accepted Sample Type
Recommended Amount
Shipment Method
Recommended Extraction Protocol
Plasma
>100ul
Dry ice
After the plasma is separated, it is taken into the appropriate tube and centrifuged at 13000 × g, 15 min, 4 °C. After centrifugation, supernatant is portioned into at least 2 tubes (or more) with 100 µl. Stored at −80 °C until analysis.
Serum
>100ul
Dry ice
After the plasma is separated, it is taken into the appropriate tube and centrifuged at 13000 × g, 15 min, 4 °C. After centrifugation, supernatant is portioned into at least 2 tubes (or more) with 100 µl. Stored at −80 °C until analysis.
Urine
>200ul
Dry ice
After the urine is collected, it is taken into the appropriate tube and centrifuged at 13000 × g, 15 min, 4 °C. After centrifugation, supernatant is portioned into at least 2 tubes (or more) with 200 µl. Stored at −80 °C until analysis.
Stool
>>50mg
Dry ice
Stored at −80 °C until analysis.
CSF
>100ul
Dry ice
Stored at −80 °C until analysis.
Saliva
>100ul
Dry ice
Stored at −80 °C until analysis.
Tissue
>50mg
Dry ice
Stored at −80 °C until analysis.
Cell Pellet
>10⁷ cells
Dry ice
Stored at −80 °C until analysis.
What we do with your samples
Once your samples arrive at Phenome Omics, we start by performing a reception control step in which we make sure the samples meet our requirements.
If the samples fail this quality control step, we will contact you to discuss possible options. If the samples pass reception control, we will inform you and the samples will be queued for sample preparations.
In our laboratory, sample preparation, metabolite identification and data analysis for global metabolomics are performed with state-of-the-art systems. We aim to acquire as much metabolic information as possibble from just a few microliters of sample material.
We use Thermo Scientific Orbitrap Exploris 240 MS for Untargeted Metabolomics Analysis.
This system offers the following qualifications:
· Exceptional mass accuracy
· Ultra-high resolution up to 240k
· Regular & Mild trapping
· Extended low mass to m/z 40
· Robust instrument performance
· AcquireX intelligent acquisition
By means of this technology we are able to use AcquireX Deep Scan for low abundance compounds.
After the metabolomics data is acquired from mass spectrometry, Compound Discoverer 3.3 software is used for data processing. Through the instrumentality of this software, feature detection with integrated databases & spectral library, data reduction, unknown annotations, statistics, pathway mappings are able to carry out.
What can Metabolomics based testing reveal about your health?
Metabolomics testing provides a window into a wide range of physiological processes that can be disrupted in illness and corrected with diet, nutrition, and lifestyle interventions.
Some metabolites have been shown to be associated with various diseases. With metabolite analysis, precautions can be taken before diseases occur.
With the obtained results – detection of increased or decreased metabolites in the blood – we can provide actionable recomendations to you about your lifestyle such as daily diet, exercise frequency, and avoiding stressful environmental conditions.
Science & Innovation
Awards
Omics Library
Language
English
Contact Us
Phenome Omics © 2026
Untargeted Metabolomics
Detection and quantification of small molecules in your biological fluids and tissue samples
Untargeted Metabolomics Analysis
Metabolites are essential components in all living organisms, and they represent a diverse group of chemical compounds such as amino acids, lipids, organic acids and environmental chemicals. Thousands of metabolites originate from the foods we eat, the microbes in our bodies and many chemical processes that are ongoing in our bodies. It is well known that disorders in metabolite patterns cause metabolic diseases that can have dramatic effects on the survival of the organism.
Therefore, is measuring metabolites essential in today’s clinical chemistry. In addition to use metabolite profiles for screening of metabolic disorders (clinical chemistry applications), targeted or untargeted profiling of metabolites or lipids are necessary also to understand fundamental biological processes. As metabolites can be considered as “endpoints” and closer to the phenotype than e.g., transcript data, metabolite data provides biochemical information that can be linked to particular phenotypes. These links can then be used to connect to gene-, protein- or other meta-data in explorations of targeted biological processes, or also suggested to identify biomarkers.
Metabolomics is to detect and quantify small molecules in biological fluids and tissues. LC-MS global metabolomics platform provides a high-fidelity, reproducible analysis of the current-state of a biological system to help identify pharmacodynamic, efficacy and response biomarkers and reveal changes in key biological pathways.
Service summary
The LC-MS technology involves use of an UHPLC, wherein the individual components in a mixture are first separated followed by ionization and separation of the ions on the basis of their mass/charge (m/z) ratio. LC-MS/MS based Orbitrap technology is used in the Metabolomics test.
- Literature based sample preparation from transferred samples
- Analyzing with Thermo Scientific Orbitrap Exploris 240 MS system
- Metabolite identification with appropriate database using Compound Discoverer software
- Data processing via Compound Discoverer 3.3 software
- Turnover time approx. 2 to 3 weeks**
Sample requirements
Accepted Sample Type
Recommended Amount
Shipment Method
Recommended Extraction Protocol
Plasma
>100ul
Dry ice
After the plasma is separated, it is taken into the appropriate tube and centrifuged at 13000 × g, 15 min, 4 °C. After centrifugation, supernatant is portioned into at least 2 tubes (or more) with 100 µl. Stored at −80 °C until analysis.
Serum
>100ul
Dry ice
After the plasma is separated, it is taken into the appropriate tube and centrifuged at 13000 × g, 15 min, 4 °C. After centrifugation, supernatant is portioned into at least 2 tubes (or more) with 100 µl. Stored at −80 °C until analysis.
Urine
>200ul
Dry ice
After the urine is collected, it is taken into the appropriate tube and centrifuged at 13000 × g, 15 min, 4 °C. After centrifugation, supernatant is portioned into at least 2 tubes (or more) with 200 µl. Stored at −80 °C until analysis.
Stool
>>50mg
Dry ice
Stored at −80 °C until analysis.
CSF
>100ul
Dry ice
Stored at −80 °C until analysis.
Saliva
>100ul
Dry ice
Stored at −80 °C until analysis.
Tissue
>50mg
Dry ice
Stored at −80 °C until analysis.
Cell Pellet
>10⁷ cells
Dry ice
Stored at −80 °C until analysis.
What we do with your samples
Once your samples arrive at Phenome Omics, we start by performing a reception control step in which we make sure the samples meet our requirements.
If the samples fail this quality control step, we will contact you to discuss possible options. If the samples pass reception control, we will inform you and the samples will be queued for sample preparations.
In our laboratory, sample preparation, metabolite identification and data analysis for global metabolomics are performed with state-of-the-art systems. We aim to acquire as much metabolic information as possibble from just a few microliters of sample material.
We use Thermo Scientific Orbitrap Exploris 240 MS for Untargeted Metabolomics Analysis.
This system offers the following qualifications:
· Exceptional mass accuracy
· Ultra-high resolution up to 240k
· Regular & Mild trapping
· Extended low mass to m/z 40
· Robust instrument performance
· AcquireX intelligent acquisition
By means of this technology we are able to use AcquireX Deep Scan for low abundance compounds.
After the metabolomics data is acquired from mass spectrometry, Compound Discoverer 3.3 software is used for data processing. Through the instrumentality of this software, feature detection with integrated databases & spectral library, data reduction, unknown annotations, statistics, pathway mappings are able to carry out.
What can Metabolomics based testing reveal about your health?
Metabolomics testing provides a window into a wide range of physiological processes that can be disrupted in illness and corrected with diet, nutrition, and lifestyle interventions.
Some metabolites have been shown to be associated with various diseases. With metabolite analysis, precautions can be taken before diseases occur.
With the obtained results – detection of increased or decreased metabolites in the blood – we can provide actionable recomendations to you about your lifestyle such as daily diet, exercise frequency, and avoiding stressful environmental conditions.
Science & Innovation
Awards
Omics Library
Language
English
Contact Us
Phenome Omics © 2026